Loading
A phase 2 trial of trastuzumab deruxtecan, durvalumab, panitumumab, botensilimab and other drugs in colorectal cancer, run by Gruppo Oncologico del Nord-Ovest, now recruiting.
Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN) is a phase 2, interventional study registered as NCT05845450 by Gruppo Oncologico del Nord-Ovest, with a registry enrolment figure of 197 participants, started 2023-05-11 and due to reach its primary completion in 2027-05. Interventions recorded: Trastuzumab deruxtecan; Durvalumab; Panitumumab; Botensilimab; Balstilimab; Sotorasib; Vorbipiprant; Nivolumab; Amivantamab; Botensilimab; Balstilimab. Conditions listed: Colorectal Cancer; Resectable Colorectal Carcinoma. Primary outcome: major pathological response rate. Colorectal eligibility wording from the registry: "* Histologically confirmed colorectal cancer adenocarcinoma that is judged as initially resectable with elective surgery aimed at radical intent with R0 margins as per multidisciplinary team assessment". Sites: Italy. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Botensilimab, Balstilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/