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A phase 2 trial of retlirafusp alfa, SHR-8068, cAPOX (capecitabine, oxaliplatin) and cetuximab in colorectal cancer, run by Fudan University, not yet recruiting.
Umbrella Trial of Neoadjuvant Therapy for Locally Advanced Colorectal Cancer is a phase 2, randomised interventional study registered as NCT07503639 by Fudan University, with a registry enrolment figure of 134 participants, started 2026-04 and due to reach its primary completion in 2028-04. Interventions recorded: SHR-1701; SHR-8068; Short-course radiotherapy; XELOX (Capecitabine and Oxaliplatin); PD-L1 antibody; cetuximab β; HRS-7058; HRS-4642. Conditions listed: Locally Advanced Colorectal Cancer. Primary outcome: Complete response (CR) rate: rate of complete response (CR), including the rate of pathologic complete response (pCR) after surgery and the rate of cCR with W&W strategy.. Colorectal eligibility wording from the registry: "Stage II/III colon cancer, or stage II/III rectal cancer located less than 10 cm from the anal verge;". No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Cetuximab, Platinum agents, Monoclonal antibodies, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
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