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A phase 2 trial of cAPOX (capecitabine, oxaliplatin) and capecitabine in colorectal cancer, run by Hebei Medical University Fourth Hospital, now recruiting.
Radiotherapy + Systemic Therapy as Conversion Therapy for pMMR/MSS T4M0 Colon Cancer（Neo-Color） is a phase 2, randomised interventional study registered as NCT06949111 by Hebei Medical University Fourth Hospital, with a registry enrolment figure of 128 participants, started 2025-05-15 and due to reach its primary completion in 2028-05-30. Interventions recorded: radiotherapy; CAPOX; Capecitabine; Iparomlimab and Tuvonralimab Injection. Conditions listed: Colon Cancer. Primary outcome: Tumor Complete Response (CR) Rate. Colorectal eligibility wording from the registry: "Histopathologically confirmed diagnosis of colon adenocarcinoma (including mucinous adenocarcinoma), identified as pMMR/MSS type; the primary tumor site must be specified (left colon defined as from the splenic flexure to the rectosigmoid junction, right colon defined as from the cecum to the proxim". Sites: China. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares CAPOX (capecitabine, oxaliplatin), Capecitabine, Platinum agents, Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Capecitabine, Platinum agents, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Capecitabine, Platinum agents, Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
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