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A phase 2 trial in colorectal cancer, run by Hebei Medical University Fourth Hospital, now recruiting.
Short-course Radiotherapy in TNT Combined With Enlonstobart for pMMR LARC is a phase 2, randomised interventional study registered as NCT07448077 by Hebei Medical University Fourth Hospital, with a registry enrolment figure of 128 participants, started 2026-03-01 and due to reach its primary completion in 2026-03-01. Interventions recorded: Experimental: short-course radiotherapy and immunotherapy; Chemoradiotherapy. Conditions listed: Efficacy and Safety of Short-course Radiotherapy in Total Neoadjuvant Therapy Combined With Enlonstobart for pMMR Locally Advanced Rectal Cancer. Primary outcome: complete response Rate (pCR+cCR ). Colorectal eligibility wording from the registry: "Histologically confirmed adenocarcinoma of the colon, and umor biopsy immunohistochemistry (IHC) indicates pMMR". Sites: China. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
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