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A phase 2 trial of dexamethasone in colorectal cancer, run by Institute of Oncology Ljubljana, now recruiting.
Effect of Perioperative Lidocaine or High-Dose Dexamethasone on Immune Response in Colon Cancer Surgery (PILDI Study) is a phase 2, randomised interventional study registered as NCT07432399 by Institute of Oncology Ljubljana, with a registry enrolment figure of 100 participants, started 2025-09-01 and due to reach its primary completion in 2027-05-01. Interventions recorded: Lidocaine; Dexamethasone; Placebo. Conditions listed: Colon Cancer; Colorectal Cancer; Perioperative Immune Response. Primary outcome: Change in Serum Cytokine Concentrations (IL-6, IL-8, IL-10, TNF-alpha). Colorectal eligibility wording from the registry: "* Histologically confirmed colon cancer". Sites: Slovenia. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
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