Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer

Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer is a phase 2, interventional study registered as NCT07407647 by Ohio State University Comprehensive Cancer Center, with a registry enrolment figure of 25 participants, started 2026-03-12 and due to reach its primary completion in 2026-12-31. Interventions recorded: Biospecimen Collection; Prasterone; Survey Administration. Conditions listed: Anal Carcinoma; Cervical Carcinoma; Malignant Female Reproductive System Neoplasm; Rectal Carcinoma; Vaginal Carcinoma; Vulvar Carcinoma. Primary outcome: Incidence of grade 2 or higher adverse events. Colorectal eligibility wording from the registry: "* Any patient with anal, rectal, cervical, vaginal, or vulvar cancer receiving external beam radiation alone, or both external beam radiation and brachytherapy with curative intent (Participants will be consented and enrolled prior to starting treatment but will not receive intervention till after t". Sites: United States. No results are recorded here; the registry entry is the source.