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A phase 2 trial in colorectal cancer, run by AHS Cancer Control Alberta, now recruiting.
Prophylactic Mesalamine to Prevent Colitis Following Treatment With Ipilimumab/Nivolumab (Ipi/Nivo) is a phase 2, interventional study registered as NCT05663775 by AHS Cancer Control Alberta, with a registry enrolment figure of 20 participants, started 2024-08-20 and due to reach its primary completion in 2026-08. Interventions recorded: Mesalamine. Conditions listed: Immune-related Adverse Event; Diarrhea; Advanced Melanoma; Advanced Rectal Carcinoma. Primary outcome: Incidence of Treatment Related Diarrhea; Severity of Treatment Related Diarrhea; Causality of Treatment Related Diarrhea. Colorectal eligibility wording from the registry: "WOCBP is defined as any female who has experienced menarche and who has not undergone surgical sterilization (hysterectomy or bilateral oophorectomy or bilateral salpingectomy) and is not postmenopausal". Sites: Canada. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
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