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A phase 2 trial of carboplatin and trilaciclib in lung cancer, run by Shanghai Chest Hospital, now recruiting.
Efficacy and Safety of First-line Treatment for Extensive-stage Small Cell Lung Cancer Using a Combination Therapy of Trilaciclib, Envafolimab, Etoposide, and Carboplatin is a phase 2, randomised interventional study registered as NCT06698965 by Shanghai Chest Hospital, with a registry enrolment figure of 52 participants, started 2024-10-13 and due to reach its primary completion in 2029-10-31. Interventions recorded: Chemotherapy （Etoposide and Carboplatin）; Immunotherapy （Envafolimab）; Trilaciclib. Conditions listed: Lung Cancer, Small Cell. Primary outcome: The incidence of grade ≥ 3 neutropenia during chemotherapy treatment. Lung eligibility wording from the registry: "* Small cell lung cancer (SCLC) confirmed by histology or cytology;". Sites: China. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Simcere Pharmaceutical, Trilaciclib, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Extensive-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin and the tag lung-deep-dive.
Shares Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin, Cytotoxic chemotherapy and the tag lung-deep-dive.
Shares Extensive-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin and the tag lung-deep-dive.
Shares Extensive-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin and the tag lung-deep-dive.
Shares Trilaciclib, Lung cancer trials open today (registry snapshot), Cytotoxic chemotherapy and the tag lung-deep-dive.
Shares Extensive-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin and the tag lung-deep-dive.
Shares Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin, Cytotoxic chemotherapy and the tag lung-deep-dive.
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