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A phase 1/2 trial in colorectal cancer, run by University of Saskatchewan, not yet recruiting.
Irreversible Electroporation (NanoKnife ®) and Immunotherapy for the Treatment of Stage IV Colorectal Cancer is a phase 1/2, interventional study registered as NCT06047015 by University of Saskatchewan, with a registry enrolment figure of 12 participants, started 2025-07 and due to reach its primary completion in 2027-12. Interventions recorded: IRE plus checkpoint inhibitor; IRE plus Checkpoint Inhibitor plus CpG-ODN. Conditions listed: Liver Metastasis Colon Cancer. Primary outcome: Complications; Complications; Abscopal effect: percent change in non-treated colorectal liver metastasis.. Colorectal eligibility wording from the registry: "Biopsy-proven colorectal liver metastases with at least one measuring \< 3". No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
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