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A phase 2 trial of capecitabine, fluorouracil (5-FU), leucovorin (folinic acid), fOLFOX (5-FU, leucovorin, oxaliplatin) and other drugs in colorectal cancer, run by Fudan University, now recruiting.
The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal Cancer is a phase 2, interventional study registered as NCT05628038 by Fudan University, with a registry enrolment figure of 93 participants, started 2022-11-30 and due to reach its primary completion in 2024-12-01. Interventions recorded: PD-1 antibody; Capecitabine; 5FU; folinic acid; Oxaliplatin; Irinotecan; Raltitrexed; Cetuximab; Bevacizumab; Radiation. Conditions listed: Recurrent Rectal Cancer. Primary outcome: Local objective response rate. Sites: China. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Bevacizumab (glioblastoma use), FOLFIRI (5-FU, leucovorin, irinotecan), Leucovorin (folinic acid), Cetuximab and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Leucovorin (folinic acid), Cetuximab, FOLFOX (5-FU, leucovorin, oxaliplatin) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFIRI (5-FU, leucovorin, irinotecan), Cetuximab, FOLFOX (5-FU, leucovorin, oxaliplatin) and the tag colorectal-deep-dive.
Shares FOLFIRI (5-FU, leucovorin, irinotecan), Leucovorin (folinic acid), FOLFOX (5-FU, leucovorin, oxaliplatin), Fluorouracil (5-FU) and the tag colorectal-deep-dive.
Shares Raltitrexed, FOLFIRI (5-FU, leucovorin, irinotecan), FOLFOX (5-FU, leucovorin, oxaliplatin), Fluorouracil (5-FU) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFIRI (5-FU, leucovorin, irinotecan), Cetuximab, Fluorouracil (5-FU) and the tag colorectal-deep-dive.
Shares FOLFIRI (5-FU, leucovorin, irinotecan), FOLFOX (5-FU, leucovorin, oxaliplatin), Topoisomerase-I inhibitors (and ADC payloads), Capecitabine and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFIRI (5-FU, leucovorin, irinotecan), Leucovorin (folinic acid), FOLFOX (5-FU, leucovorin, oxaliplatin) and the tag colorectal-deep-dive.
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