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A phase 3 trial of Apalutamide, Degarelix, Fluciclovine F-18, Goserelin / leuprolide, Leuprolide, Relugolix and Triptorelin in Prostate cancer, run by ECOG-ACRIN Cancer Research Group, now recruiting.
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging is a phase 3 interventional study registered as NCT04423211 by ECOG-ACRIN Cancer Research Group, with 804 participants planned, started 2020-10-08 and due to reach its primary completion in 2032-12-31. Interventions recorded: 3-Dimensional Conformal Radiation Therapy, Apalutamide, Computed Tomography, Degarelix, External Beam Radiation Therapy, Fluciclovine F18, Goserelin Acetate, Intensity-Modulated Proton Therapy, Intensity-Modulated Radiation Therapy, Leuprolide Acetate, Magnetic Resonance Imaging, Positron Emission Tomography, Quality-of-Life Assessment, Questionnaire Administration, Relugolix, Stereotactic Body Radiation Therapy, Triptorelin, Volume Modulated Arc Therapy. Conditions recorded: Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Carcinoma, Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8.
Linked to the drug Fluciclovine F-18 because the registry names it among its interventions and Prostate cancer among its conditions. Registry record only: no result has been read by an editor.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Relugolix, Degarelix, Triptorelin, Apalutamide and the tag pipeline.
Shares Relugolix, Degarelix, Triptorelin, Leuprolide (leuprorelin) and GnRH agonists and the tag pipeline.
Shares Goserelin / leuprolide (ovarian function suppression), Leuprolide (leuprorelin) and GnRH agonists, ECOG-ACRIN Cancer Research Group, Prostate cancer and the tag pipeline.
Shares Degarelix, Triptorelin, Goserelin / leuprolide (ovarian function suppression), Leuprolide (leuprorelin) and GnRH agonists and the tag pipeline.
Shares Degarelix, Triptorelin, Goserelin / leuprolide (ovarian function suppression), Prostate cancer and the tag pipeline.
Shares Degarelix, Goserelin / leuprolide (ovarian function suppression), Prostate cancer and the tag pipeline.
Shares Degarelix, Goserelin / leuprolide (ovarian function suppression), Prostate cancer and the tag pipeline.
Shares Goserelin / leuprolide (ovarian function suppression), Leuprolide (leuprorelin) and GnRH agonists, Biochemical recurrence of prostate cancer, Prostate cancer and the tag pipeline.
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