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A phase 3 trial of Bicalutamide, Flutamide, Goserelin / leuprolide, Buserelin, Triptorelin and Degarelix in Prostate cancer, run by Radiation Therapy Oncology Group, completed.
Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer is a phase 3 interventional study registered as NCT00936390 by Radiation Therapy Oncology Group, with 1538 participants recorded, started 2009-09 and reaching its primary completion in 2020-10-03. Interventions recorded: bicalutamide, flutamide, LHRH agonist (antagonist) therapy, Dose-Escalated Radiation Therapy. Conditions recorded: Prostate Cancer.
Linked to the drug Buserelin because the registry names it among its interventions and Prostate cancer among its conditions. Registry record only: no result has been read by an editor.
Numbers are from the trial as recorded here; see the source links in the table below. This is orientation, not medical advice: ask your team how closely the trial population matches you.
1,538 enrolled.
95% CI 87.7 to 92.2; Figures from the ClinicalTrials.gov results section (first posted 2022-10-06), not from a publication · 95% CI 88.8 to 93.1
Source| Endpoint | Arm | n | Value | HR (95% CI) | p | Source |
|---|---|---|---|---|---|---|
| Percentage of Participants Alive (Overall Survival)primary | Dose-Escalated Radiation Therapy Alone | 750 | 90% | 0.85 (0.65 to 1.11) | 0.22 | link |
| Dose-Escalated Radiation Therapy and Short-Term Androgen-Deprivation | 742 | 91% |
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Buserelin, Flutamide, Degarelix, Triptorelin and the tag pipeline.
Shares Buserelin, Flutamide, Triptorelin, Bicalutamide and the tag pipeline.
Shares Buserelin, Flutamide, Bicalutamide, Goserelin / leuprolide (ovarian function suppression) and the tag pipeline.
Shares Flutamide, Degarelix, Triptorelin, Bicalutamide and the tag pipeline.
Shares Degarelix, Bicalutamide, Goserelin / leuprolide (ovarian function suppression), Prostate cancer and the tag pipeline.
Shares Degarelix, Bicalutamide, Goserelin / leuprolide (ovarian function suppression), Prostate cancer and the tag pipeline.
Shares Buserelin, Flutamide, Bicalutamide, Goserelin / leuprolide (ovarian function suppression) and the tag pipeline.
Shares Flutamide, Triptorelin, Prostate cancer and the tag pipeline.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/