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A phase 3 trial in lung cancer, run by SWOG Cancer Research Network, active but no longer recruiting.
S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer is a phase 3, randomised interventional study registered as NCT04155034 by SWOG Cancer Research Network, with a registry enrolment figure of 668 participants, started 2020-05-04 and due to reach its primary completion in 2026-03-17. Interventions recorded: Magnetic Resonance Imaging; Prophylactic Cranial Irradiation. Conditions listed: Extensive Stage Lung Small Cell Carcinoma; Limited Stage Lung Small Cell Carcinoma; Lung Small Cell Carcinoma. Primary outcome: Overall survival (OS). Lung eligibility wording from the registry: "* Patient must have a histologically confirmed diagnosis of small-cell lung cancer (SCLC)". Sites: Canada, Chile, Colombia, Mexico, Saudi Arabia, South Korea, United States. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Limited-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag lung-deep-dive.
Shares Limited-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag lung-deep-dive.
Shares Extensive-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag lung-deep-dive.
Shares Limited-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag lung-deep-dive.
Shares Extensive-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag lung-deep-dive.
Shares Extensive-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag lung-deep-dive.
Shares Limited-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag lung-deep-dive.
Shares Limited-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag lung-deep-dive.
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