A phase 3 trial of Amsacrine, Asparaginase, Cytarabine, Daunorubicin, Etoposide, Methotrexate and Mitoxantrone in Leukaemia and Myelodysplastic syndromes / neoplasms, run by Medical Research Council, completed.
Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myeloid Leukemia is a phase 3 interventional study registered as NCT00003436 by Medical Research Council, with 2000 participants recorded, started 1998-07. Interventions recorded: amsacrine, asparaginase, cytarabine, daunorubicin hydrochloride, etoposide, methotrexate, mitoxantrone hydrochloride, therapeutic hydrocortisone, allogeneic bone marrow transplantation. Conditions recorded: Leukemia, Myelodysplastic Syndromes.
Linked to the drug Amsacrine because the registry names it among its interventions and Leukaemia and Myelodysplastic syndromes / neoplasms among its conditions. Registry record only: no result has been read by an editor.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Amsacrine, MRC Clinical Trials Unit at UCL, Mitoxantrone, Daunorubicin and the tag pipeline.
Shares Mitoxantrone, Daunorubicin, Asparaginase (pegaspargase, calaspargase pegol, Erwinia asparaginase), Cytarabine and the tag pipeline.
Shares Amsacrine, Mitoxantrone, Cytarabine, Etoposide and the tag pipeline.
Shares Mitoxantrone, Daunorubicin, Cytarabine, Etoposide and the tag pipeline.
Shares Mitoxantrone, Daunorubicin, Asparaginase (pegaspargase, calaspargase pegol, Erwinia asparaginase), Cytarabine and the tag pipeline.
Shares Daunorubicin, Asparaginase (pegaspargase, calaspargase pegol, Erwinia asparaginase), Cytarabine, Methotrexate and the tag pipeline.
Shares Daunorubicin, Asparaginase (pegaspargase, calaspargase pegol, Erwinia asparaginase), Cytarabine, Methotrexate and the tag pipeline.
Shares Daunorubicin, Cytarabine, Etoposide and the tag pipeline.
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