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Ionis Pharmaceuticals
Ionis is the Carlsbad company that made antisense oligonucleotides into medicines; its cancer programmes, including the clusterin antisense custirsen developed with OncoGenex and the STAT3 antisense danvatirsen, reached late trials without approval.
Also called: Ionis Pharmaceuticals, Inc.Isis Pharmaceuticals
Overview
Ionis Pharmaceuticals, founded in 1989 as Isis Pharmaceuticals and based in Carlsbad, California, pioneered antisense oligonucleotide drugs, with approvals in spinal muscular atrophy, transthyretin amyloidosis and other rare diseases through partners. In oncology it co-developed custirsen (OGX-011), whose phase 3 trials failed, and tested the STAT3 antisense danvatirsen with checkpoint inhibitors through AstraZeneca. ClinicalTrials.gov lists Ionis as lead sponsor of a phase 3 cancer trial.
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Sources
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
ClinicalTrials.gov · 1
ionispharma.com · 1
wikidata.org · 1
A source that has moved or gone is reported by the weekly link check. /audit/
ProvenanceLast edited 2026-09-18 · Jude Gomila · Add Wikidata ids and Wikipedia links for 80 more companies · diff · file
Sourced, not expert-reviewed