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The trial testing a thing the NHS already does without evidence: giving radiotherapy after surgery for a high-risk squamous cell carcinoma, to stop it coming back.
Adjuvant radiotherapy after excision of a high-risk cutaneous squamous cell carcinoma is widely offered in the UK and has never been tested in a randomised trial. SCC-AFTER, sponsored by Cardiff University with a target of 840 participants and a registered end date of 1 January 2031, is the trial. Together with SPOT-IT and EXCISE it makes Cardiff the centre of British keratinocyte cancer trials, which is itself worth noticing: the commonest cancers in the country have almost no randomised evidence base, and most of what is being built is being built in Wales.
Criteria as posted are in the stored snapshot. Read 2026-10-07.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Velindre Cancer Centre, Cutaneous squamous cell carcinoma, Skin cancer (all types) and the tags uk, skin, recruiting.
Shares Cutaneous squamous cell carcinoma, Skin cancer (all types) and the tags uk, skin.
Shares Cutaneous squamous cell carcinoma, Skin cancer (all types) and the tags uk, skin.
Shares Cutaneous squamous cell carcinoma, Skin cancer (all types) and the tag uk.
Shares Skin cancer (all types) and the tags uk, skin, recruiting.
Shares Skin cancer (all types) and the tags uk, skin.
Shares Skin cancer (all types) and the tags uk, skin.
Shares Skin cancer (all types) and the tags uk, skin.
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