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A phase 3 trial testing PF-08046054 in non-small-cell lung cancer, now recruiting.
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC) is a phase 3 interventional study registered as NCT07144280, led by Pfizer, and recruiting on the registry. Official title: PADL1NK-005: A Randomised, Phase 3, Open-Label Study to Evaluate PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC). Planned enrolment is 680 participants (estimated). The study started in 2025-09-29 and primary completion is expected in 2028-03-10. No results have been posted on ClinicalTrials.gov.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares PF-08046054, Pfizer (incl. Seagen), Non-small-cell lung cancer.
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