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A phase 2 trial of trastuzumab emtansine, trastuzumab deruxtecan, datopotamab deruxtecan, sacituzumab govitecan and other drugs in pancreatic cancer, run by Fudan University, not yet recruiting.
Protein-Matched ADC or PDC Umbrella Trial in Advanced Pancreatic and Breast Cancer is a phase 2, interventional study registered as NCT07825753 by Fudan University, with a registry enrolment figure of 225 participants, started 2026-09-10 and due to reach its primary completion in 2027-09-01. Interventions recorded: Trastuzumab emtansine (T-DM1); Trastuzumab deruxtecan (T-DXd); Datopotamab deruxtecan (Dato-DXd); Sacituzumab govitecan (SG); Enfortumab vedotin (EV); Becotatug vedotin (MRG003); Izalontamab brengitecan (iza-bren / BL-B01D1); Mirvetuximab soravtansine (MIRV). Conditions listed: Advanced or Metastatic Pancreatic Adenocarcinoma; Advanced or Metastatic Breast Cancer (BC). Primary outcome: Objective Response Rate (ORR) as Assessed by RECIST 1.1. Pancreatic eligibility wording from the registry: "Histologically confirmed recurrent (unresectable) or metastatic advanced pancreatic cancer or breast cancer". Sites: China. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Trastuzumab deruxtecan, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma, Antibody-drug conjugate (ADC) and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
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