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A phase 3 trial of cabozantinib, zanzalintinib, atezolizumab, nivolumab and other drugs in colorectal cancer, run by Exelixis, now recruiting.
Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study is a phase 3, interventional study registered as NCT07620574 by Exelixis, with a registry enrolment figure of 5000 participants, started 2026-07-30 and due to reach its primary completion in 2030-05-31. Interventions recorded: Cabozantinib; Zanzalintinib; Atezolizumab; Nivolumab; Abiraterone; Prednisone; Enzalutamide. Conditions listed: Cancer; Renal Cell Carcinoma (RCC); Pancreatic Neuroendocrine Tumors (pNET); Extra-Pancreatic NET (epNET); Hepatocellular Carcinoma (HCC); Differentiated Thyroid Cancer (DTC); Non-Clear Cell Renal Cell Carcinoma (nccRCC); Colorectal Cancer; Prostate Cancer. Primary outcome: Number of Participants With Treatment Emergent Adverse Events (TEAEs). Sites: United States. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Zanzalintinib, Exelixis, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Exelixis, Cabozantinib, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Bristol Myers Squibb, Nivolumab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Zanzalintinib, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Atezolizumab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Nivolumab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Nivolumab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Nivolumab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
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