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Trials
Adebrelimab Plus S-1 for Resected Cholangiocarcinoma

Adebrelimab Plus S-1 for Resected Cholangiocarcinoma

A phase 2 trial of adebrelimab and S-1 in gallbladder cancer and other biliary tract cancers, run by Xingjun Guo, not yet recruiting.

Planned

Overview Taking part Connected8

Overview

Adebrelimab Plus S-1 for Resected Cholangiocarcinoma is a phase 2 interventional study registered as NCT07561775 by Xingjun Guo, with a registry enrolment figure of 40 participants, started 2026-04-21 and due to reach its primary completion in 2028-01-01. Interventions recorded: Adebrelimab, S-1. Conditions listed: Cholangiocarcinoma, Biliary Tract Cancer. No results are recorded here; the registry entry is the source.

Setting

A Single-Arm, Exploratory Clinical Study of Adebrelimab Combined With S-1 in Patients With Resected Cholangiocarcinoma

Phase

Phase 2

Sponsor

Xingjun Guo

Registry

Started

2026-04-21 (estimated)

Enrolled

40 enrolled

Taking part

NCT07561775not yet recruiting

Run by: Xingjun Guo
Open to: 18 Years to 75 Years, any sex
Enrolment: 40 (estimated)
Registry updated: 2026-05-01

The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.

ClinicalTrials.gov data courtesy of the US National Library of Medicine.

Connected

8

Similar pages

Trial
Chemotherapy Combined With Adebrelimab and Mecapegfilgrastim in Neoadjuvant Treatment of Potentially Resectable BTC
Shares Adebrelimab, Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups), Biliary tract cancer (all types), Biliary tract cancer (cholangiocarcinoma) and the tag gallbladder-deep-dive.
Trial
A Study of HRS-4642 Monotherapy or in Combination With Adebrelimab in the Treatment of Advanced Biliary Tract Tumors.
Shares Adebrelimab, Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups), Biliary tract cancer (all types), Biliary tract cancer (cholangiocarcinoma) and the tag gallbladder-deep-dive.
Trial
A Single-arm, Multicenter, Exploratory Study of Adebrelimab Combined With Apatinib and Systemic Chemotherapy for Initially Unresectable Biliary Tract Cancer
Shares Adebrelimab, Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups), Biliary tract cancer (all types), Biliary tract cancer (cholangiocarcinoma) and the tag gallbladder-deep-dive.
Trial
An Open-label, Single-arm, Multicenter Exploratory Study of Adebrelimab Combined With Gemcitabine and Albumin-bound Paclitaxel as First-line Treatment for Biliary Tract Malignancies
Shares Adebrelimab, Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups), Biliary tract cancer (all types), Biliary tract cancer (cholangiocarcinoma) and the tag gallbladder-deep-dive.
Trial
Durvalumab Combined With S-1 as Adjuvant Therapy of Resectable BTC
Shares Tegafur, gimeracil and oteracil (S-1), Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups), Biliary tract cancer (all types), Biliary tract cancer (cholangiocarcinoma) and the tag gallbladder-deep-dive.
Trial
Camrelizumab Plus Apatinib in Combination With GEMOX (Gemcitabine and Oxaliplatin ) in Patients With Locally Advanced Biliary Tract Cancer
Shares Tegafur, gimeracil and oteracil (S-1), Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups), Biliary tract cancer (all types), Biliary tract cancer (cholangiocarcinoma) and the tag gallbladder-deep-dive.
Trial
Chemotherapy Combined With Adebrelimab and Apatinib as the Perioperative Treatment in Patients With Biliary Tract Cancer
Shares Adebrelimab, Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups), Biliary tract cancer (all types), Biliary tract cancer (cholangiocarcinoma) and the tag gallbladder-deep-dive.
Trial
Neoadjuvant Tislelizumab, Gemcitabine, Cisplatin and S-1 for Resectable High-risk Cholangiocarcinoma
Shares Tegafur, gimeracil and oteracil (S-1), Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups), Biliary tract cancer (all types), Biliary tract cancer (cholangiocarcinoma) and the tag gallbladder-deep-dive.

cancers

Biliary tract cancer (all types)Biliary tract cancer (cholangiocarcinoma)Gallbladder cancer

technologies

Cytotoxic chemotherapy Immune checkpoint inhibitors

drugs

ApprovedMonoclonal antibody (anti-PD-L1, humanised IgG4)

Adebrelimab · Arelili

ApprovedOral fluoropyrimidine combination (antimetabolite)

Tegafur, gimeracil and oteracil (S-1) · Teysuno

terms

Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups)

Evidence strength28/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
40 enrolled+8
No structured primary endpoint0
Result: planned0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

gallbladder-deep-dive

Make correction

Report a readout

Cancers

Gallbladder cancer
Biliary tract cancer (cholangiocarcinoma)
Biliary tract cancer (all types)

Technologies

Immune checkpoint inhibitors
Cytotoxic chemotherapy

Products

Adebrelimab
Tegafur, gimeracil and oteracil (S-1)

Sources

Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.

ClinicalTrials.gov · 1

ClinicalTrials.gov NCT07561775

A source that has moved or gone is reported by the weekly link check. /audit/

ProvenanceLast edited 2026-09-24 · Jude Gomila · Gallbladder cancer treatments and trials · diff · file

Sourced, not expert-reviewed

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