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A phase 3 trial of cetuximab and bevacizumab (glioblastoma use) in colorectal cancer, run by Sixth Affiliated Hospital, Sun Yat-sen University, now recruiting.
SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC is a phase 3, randomised interventional study registered as NCT07549399 by Sixth Affiliated Hospital, Sun Yat-sen University, with a registry enrolment figure of 204 participants, started 2026-05-20 and due to reach its primary completion in 2029-04-30. Interventions recorded: Short-Course Radiotherapy; PD-1 monoclonal antibody; mFOLFOX6 regimen; Cetuximab; Bevacizumab; Surgical resection. Conditions listed: Rectal Adenocarcinoma; High-Risk Cancer; MSS. Primary outcome: 3 years DFS Rate. Colorectal eligibility wording from the registry: "Histologically or cytologically confirmed pMMR/MSS rectal adenocarcinoma; all other histological types are excluded". Sites: China. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Bevacizumab (glioblastoma use), Cetuximab, Monoclonal antibodies, Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Cetuximab, Monoclonal antibodies, Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Cetuximab, Monoclonal antibodies, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Cetuximab, Monoclonal antibodies, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
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