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A phase 2 trial of sintilimab in colorectal cancer, run by Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, now recruiting.
Tolecizumab Plus Chemoimmunotherapy for pMMR/MSS Locally Advanced Colon Adenocarcinoma is a phase 2, randomised interventional study registered as NCT07468630 by Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, with a registry enrolment figure of 106 participants, started 2026-04-10 and due to reach its primary completion in 2026-12-31. Interventions recorded: Tolecizumab (PCSK9 Inhibitor); Sintilimab. Conditions listed: Colon Adenocarcinoma. Primary outcome: pCR. Colorectal eligibility wording from the registry: "Pathohistologically confirmed colon adenocarcinoma with cT3c stage or above". Sites: China. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Sintilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Sintilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Sintilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Sintilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Sintilimab, Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Sintilimab, Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Sintilimab, Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Immune checkpoint inhibitors and the tag colorectal-deep-dive.
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