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A phase 3 trial of pemetrexed, carboplatin, cisplatin and tislelizumab in lung cancer, run by Shanghai Huaota Biopharmaceutical Co., Ltd., not yet recruiting.
Phase III Clinical Study of HB0025 Combined With Chemotherapy Versus Tislelizumab Combined With Chemotherapy as First-Line Treatment for Advanced Nonsquamous Non-Small Cell Lung Cancer is a phase 3, randomised interventional study registered as NCT07383116 by Shanghai Huaota Biopharmaceutical Co., Ltd., with a registry enrolment figure of 500 participants, started 2026-01-15 and due to reach its primary completion in 2028-04-10. Interventions recorded: Pemetrexed injection; Carboplatin Injection; Cisplatin injection; HB0025 Injection; Tislelizumab. Conditions listed: Non Squamous Non-small Cell Lung Cancer. Primary outcome: Progression-free survival (PFS). Lung eligibility wording from the registry: "Histologically or cytologically confirmed locally advanced (Stage IIIB/IIIC) or metastatic (Stage IV) non-squamous non-small cell lung cancer (NSCLC) (confirmed per the 9th Edition of the TNM Staging System for Lung Cancer by the Union for International Cancer Control \[UICC\] and the American Joint". Sites: China. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Tislelizumab, Pemetrexed, Lung cancer trials open today (registry snapshot), Platinum agents and the tag lung-deep-dive.
Shares Tislelizumab, Pemetrexed, Lung cancer trials open today (registry snapshot), Platinum agents and the tag lung-deep-dive.
Shares Tislelizumab, Lung cancer trials open today (registry snapshot), Platinum agents, Cisplatin and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Platinum agents, Cisplatin and the tag lung-deep-dive.
Shares Tislelizumab, Pemetrexed, Lung cancer trials open today (registry snapshot), Platinum agents and the tag lung-deep-dive.
Shares Tislelizumab, Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Platinum agents, Cisplatin and the tag lung-deep-dive.
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