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A phase 2 trial of zanidatamab in colorectal cancer, run by UNICANCER, now recruiting.
Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene. is a phase 2, interventional study registered as NCT07192068 by UNICANCER, with a registry enrolment figure of 105 participants, started 2025-10-30 and due to reach its primary completion in 2028-03-13. Interventions recorded: Zanidatamab. Conditions listed: Non-Small Cell Lung Cancer; Sarcoma; Head &Amp; Neck Cancer; Colorectal Carcinoma; Endometrial. Primary outcome: Confirmed Objective Response Rate (ORR) by investigator. Colorectal eligibility wording from the registry: "Histologically or cytologically confirmed endometrial, colorectal, head \& neck, non-small cell lung cancer (NSCLC), or sarcoma". Sites: France. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Zanidatamab, HER2-amplified colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares UNICANCER, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares UNICANCER, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares HER2-amplified colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares HER2-amplified colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares HER2-amplified colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares HER2-amplified colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Jazz Pharmaceuticals, Zanidatamab, HER2-amplified colorectal cancer, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
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