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A phase 2 trial of bevacizumab (glioblastoma use) and encorafenib in colorectal cancer, run by Vall d'Hebron Institute of Oncology, not yet recruiting.
A Study to Characterize Encorafenib Plus Cetuximab as Rechallenge Treatment for BRAF V600E-mutant Metastatic Colorectal Cancer Patients After Previous Therapy With BRAF Inhibitors-based Combinations is a phase 2, interventional study registered as NCT07178717 by Vall d'Hebron Institute of Oncology, with a registry enrolment figure of 25 participants, started 2025-10 and due to reach its primary completion in 2028-02. Interventions recorded: Rechalange with bevacizumab + encorafenib. Conditions listed: Colo-rectal Cancer. Primary outcome: Progression free survival. Colorectal eligibility wording from the registry: "5 x ULN is allowed if direct (conjugated) ≤1". Sites: Spain. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Encorafenib, Bevacizumab (glioblastoma use), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares BRAF V600E-mutant colorectal cancer, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares BRAF V600E-mutant colorectal cancer, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares BRAF V600E-mutant colorectal cancer, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Encorafenib, BRAF V600E-mutant colorectal cancer, Colorectal cancer trials open today (registry snapshot), Small-molecule kinase inhibitors and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
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