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A phase 2 trial in colorectal cancer, run by Federation Francophone de Cancerologie Digestive, not yet recruiting.
5-fluorouracil Plus Panitumumab (Anti-EGFR) and Sotorasib (KRAS G12C Inhibitor) in First-line Treatment of Patients Non-eligible for a Doublet/Triplet Chemotherapy With Advanced Unresectab is a phase 2, interventional study registered as NCT07124884 by Federation Francophone de Cancerologie Digestive, with a registry enrolment figure of 300 participants, started 2025-08-31 and due to reach its primary completion in 2030-06-30. Interventions recorded: Administration of experimental treatment association (sotorasib, panitumumab 5FU). Conditions listed: Colorectal Carcinoma; KRAS G12C Mutation; Unresectable Colorectal Cancer. Primary outcome: Percentage of patient alive or without progression 8 months after inclusion.. Colorectal eligibility wording from the registry: "* Histologically proven advanced-stage unresectable locally advanced or metastatic colorectal adenocarcinoma". Sites: France, Germany, Italy, Spain. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares KRAS G12C-mutant colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
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