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A phase 2 trial of bevacizumab (glioblastoma use) and cAPOX (capecitabine, oxaliplatin) in colorectal cancer, run by Peking University Cancer Hospital & Institute, not yet recruiting.
Iparomlimab/Tuvonralimab Combined With Bevacizumab and CAPEOX as Conversion Therapy for Colorectal Cancer Liver Metastasis is a phase 2, interventional study registered as NCT07007728 by Peking University Cancer Hospital & Institute, with a registry enrolment figure of 54 participants, started 2025-06-01 and due to reach its primary completion in 2026-12-31. Interventions recorded: Iparomlimab/Tuvonralimab; Bevacizumab + CAPEOX; Surgical resection ± ablation or stereotactic radiotherapy (if applicable). Conditions listed: Colorectal Neoplasms; Secondary Malignant Neoplasm of Liver. Primary outcome: Objective Response Rate. Colorectal eligibility wording from the registry: "Pathologically confirmed colorectal adenocarcinoma with liver metastases confirmed by pathology or imaging;". Sites: China. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Bevacizumab (glioblastoma use), CAPOX (capecitabine, oxaliplatin), SBRT / SABR (stereotactic radiotherapy), Platinum agents and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), CAPOX (capecitabine, oxaliplatin), Platinum agents, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Thermal ablation (RFA, microwave, cryo), SBRT / SABR (stereotactic radiotherapy), Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares CAPOX (capecitabine, oxaliplatin), Platinum agents, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), CAPOX (capecitabine, oxaliplatin), Platinum agents, Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), SBRT / SABR (stereotactic radiotherapy), Platinum agents, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Thermal ablation (RFA, microwave, cryo), CAPOX (capecitabine, oxaliplatin), Platinum agents, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Platinum agents, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
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