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A phase 2 trial of tislelizumab in colorectal cancer, run by brenner baruch, now recruiting.
Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer. is a phase 2, randomised interventional study registered as NCT06940388 by brenner baruch, with a registry enrolment figure of 134 participants, started 2025-07-23 and due to reach its primary completion in 2029-08. Interventions recorded: Tislelizumab; Total neoadjuvant therapy (TNT). Conditions listed: Locally Advanced Rectal Cancer (LARC). Primary outcome: 3-year total mesorectal excision (TME) free survival rates. Colorectal eligibility wording from the registry: "* No prior chemotherapy, immunotherapy, radiotherapy or surgery for rectal cancer". Sites: Germany, Israel. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Tislelizumab, Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Tislelizumab, Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Tislelizumab, Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Tislelizumab, Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Tislelizumab, Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Tislelizumab, Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Tislelizumab, Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Tislelizumab, Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
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