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A phase 2/3 trial in colorectal cancer, run by National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos, now recruiting.
Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. is a phase 2/3, randomised interventional study registered as NCT06758830 by National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos, with a registry enrolment figure of 400 participants, started 2025-01-06 and due to reach its primary completion in 2029-12-27. Interventions recorded: Radiation Therapy; Chemoradiotherapy; Consolidation Chemotherapy; Surgery; Part two; Adjuvant treatment. Conditions listed: Rectal Cancer; Total Neoadjuvant Treatment; Neoadjuvant Therapy; Radiotherapy; Chemotherapy; Organ Preservation; Radiotherapy Side Effect; Chemotherapy Side Effects; Chemoradiotherapy; Low Anterior Resection Syndrome; Quality of Life. Primary outcome: Postoperative complications; TNT toxicity; Mortality rate. Colorectal eligibility wording from the registry: "* Pathologically confirmed rectal adenocarcinoma". Sites: Lithuania. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
Shares Colorectal cancer trials open today (registry snapshot), Rectal cancer, IMRT / IGRT (modern external beam) and the tag colorectal-deep-dive.
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