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A phase 3 trial of cisplatin, carboplatin, pemetrexed, gemcitabine and other drugs in lung cancer, run by Alliance for Clinical Trials in Oncology, active but no longer recruiting.
Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer is a phase 3, randomised interventional study registered as NCT06632327 by Alliance for Clinical Trials in Oncology, with a registry enrolment figure of 37 participants, started 2024-12-11 and due to reach its primary completion in 2029-04-30. Interventions recorded: Surgical Procedure; Cisplatin; Carboplatin; Pemetrexed; Gemcitabine; Docetaxel; Vinorelbine; Nivolumab; Pembrolizumab; Atezolizumab; Computed Tomography; Magnetic Resonance Imaging; Positron Emission Tomography. Conditions listed: Resectable Lung Non-Small Cell Carcinoma; Stage II Lung Cancer AJCC v8; Stage IIIA Lung Cancer AJCC v8; Stage IIIB Lung Cancer AJCC v8. Primary outcome: 3-year real-world event-free survival (rwEFS); Overall survival (OS). Lung eligibility wording from the registry: "* Histologically or cytologically confirmed surgically resectable stage IIA to IIIB NSCLC according to the American Joint Committee on Cancer (AJCC) 9th edition (stage IIA to IIIB NSCLC up to single station N2, according to the AJCC 8th edition)". Sites: United States. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Resectable stage I to III non-small-cell lung cancer, Pemetrexed, Lung cancer trials open today (registry snapshot), Gemcitabine and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Gemcitabine, Nivolumab and the tag lung-deep-dive.
Shares Vinorelbine, Atezolizumab, Pemetrexed, Docetaxel and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Platinum agents, Cisplatin and the tag lung-deep-dive.
Shares Resectable stage I to III non-small-cell lung cancer, Lung cancer trials open today (registry snapshot), Nivolumab, Platinum agents and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin and the tag lung-deep-dive.
Shares Atezolizumab, Pemetrexed, Lung cancer trials open today (registry snapshot), Nivolumab and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Platinum agents, Cisplatin and the tag lung-deep-dive.
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