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A phase 2 trial of Etoposide, Carboplatin, Paclitaxel / nab-paclitaxel in small-cell lung cancer, run by BioNTech SE, active and no longer recruiting.
Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy is a phase 2 interventional study registered as NCT06449209 by BioNTech SE, with 110 participants planned, started 2024-08-05 and due to reach its primary completion in 2027-06. Interventions recorded: BNT327 Dose Level 1 (DL1), BNT327 Dose Level 2 (DL2), Etoposide, Carboplatin, Paclitaxel. Conditions listed: Extensive-stage Small-cell Lung Cancer, Small-cell Lung Cancer. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares BioNTech, Extensive-stage small-cell lung cancer, Etoposide, Small-cell lung cancer.
Shares BioNTech, Extensive-stage small-cell lung cancer, Etoposide, Carboplatin.
Shares Extensive-stage small-cell lung cancer, Etoposide, Carboplatin, Small-cell lung cancer.
Shares BioNTech, Paclitaxel / nab-paclitaxel, Carboplatin, Small-cell lung cancer.
Shares Extensive-stage small-cell lung cancer, Etoposide, Carboplatin, Small-cell lung cancer.
Shares Extensive-stage small-cell lung cancer, Etoposide, Carboplatin, Small-cell lung cancer.
Shares Extensive-stage small-cell lung cancer, Etoposide, Carboplatin, Small-cell lung cancer.
Shares Extensive-stage small-cell lung cancer, Etoposide, Carboplatin, Small-cell lung cancer.
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