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A phase 2 trial in colorectal cancer, run by Shandong Cancer Hospital and Institute, now recruiting.
Fruquintinib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Colorectal Cancer With Liver Metastases is a phase 2, randomised interventional study registered as NCT06356584 by Shandong Cancer Hospital and Institute, with a registry enrolment figure of 62 participants, started 2024-04-01 and due to reach its primary completion in 2026-10-01. Interventions recorded: Immunotherapy (Sintilimab); Targeted Therapy Agent (Fruquintinib); Radiotherapy (SBRT and LDRT). Conditions listed: Colorectal Cancer; Immunotherapy; Radiotherapy; Targeted Therapy; Liver Metastasis. Primary outcome: Progression-free survival (PFS). Colorectal eligibility wording from the registry: "* Histologically confirmed colorectal adenocarcinoma with liver metastases (8th edition AJCC)". Sites: China. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares SBRT / SABR (stereotactic radiotherapy), Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares SBRT / SABR (stereotactic radiotherapy), Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares SBRT / SABR (stereotactic radiotherapy), Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares SBRT / SABR (stereotactic radiotherapy), Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares SBRT / SABR (stereotactic radiotherapy), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares SBRT / SABR (stereotactic radiotherapy), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares SBRT / SABR (stereotactic radiotherapy), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares SBRT / SABR (stereotactic radiotherapy), Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
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