A phase 2 trial of irinotecan (and liposomal irinotecan), capecitabine and bevacizumab (glioblastoma use) in colorectal cancer, run by Harbin Medical University, not yet recruiting.
Liposomal Irinotecan and Capecitabine Plus Bevacizumab as Second-line Therapy in Metastatic Colorectal Cancer is a phase 2, interventional study registered as NCT06192680 by Harbin Medical University, with a registry enrolment figure of 63 participants, started 2024-04-01 and due to reach its primary completion in 2025-11-30. Interventions recorded: Liposomal irinotecan; Capecitabine; Bevacizumab. Conditions listed: Colorectal Cancer. Primary outcome: Progression free Survival. Colorectal eligibility wording from the registry: "* Histopathologically and/or cytologically confirmed unresectable metastatic colorectal adenocarcinoma, and patients failed or are intolerant to first-line treatment with oxaliplatin ± VEGF/EGFR". No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Irinotecan (and liposomal irinotecan), Bevacizumab (glioblastoma use), Topoisomerase-I inhibitors (and ADC payloads), Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Irinotecan (and liposomal irinotecan), Bevacizumab (glioblastoma use), Topoisomerase-I inhibitors (and ADC payloads), Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Irinotecan (and liposomal irinotecan), Topoisomerase-I inhibitors (and ADC payloads), Capecitabine, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Irinotecan (and liposomal irinotecan), Bevacizumab (glioblastoma use), Topoisomerase-I inhibitors (and ADC payloads), Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Capecitabine, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Capecitabine, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Capecitabine, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Irinotecan (and liposomal irinotecan), Topoisomerase-I inhibitors (and ADC payloads), Capecitabine, Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
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