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A phase 2 trial of Brentuximab vedotin, Cyclophosphamide, Doxorubicin and Prednisone in non-Hodgkin lymphoma, run by Takeda, active and no longer recruiting.
A Study of Brentuximab Vedotin in Combination With Cyclophosphamide, Doxorubicin (Hydroxydaunorubicin), Prednisone (CHP) in Chinese Participants With CD30-Positive (CD30+) Peripheral T-Cell Lymphomas (PTCL) is a phase 2 interventional study registered as NCT05673785 by Takeda, with 52 participants enrolled, started 2023-02-10 and due to reach its primary completion in 2025-04-27. Interventions recorded: Brentuximab Vedotin, Cyclophosphamide, Doxorubicin and Prednisone. Results have been posted on the registry.
Numbers are from the trial as recorded here; see the source links in the table below. This is orientation, not medical advice: ask your team how closely the trial population matches you.
52 enrolled.
95% CI 86.8 to 99.5; Figures from the ClinicalTrials.gov results section (first posted 2026-06-12), not from a publication
Source| Endpoint | Arm | n | Value | HR (95% CI) | p | Source |
|---|---|---|---|---|---|---|
| Overall Response Rate (ORR) by Independent Review Facility (IRF) Assessment Per Revised Response Criteria for Malignant Lymphomaprimary | Brentuximab Vedotin + CHP | 52 | 96.2% | - | - | link |
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Prednisone, Peripheral T-cell lymphomas (including cutaneous T-cell lymphoma), Doxorubicin, Cyclophosphamide and the tag pipeline.
Shares Takeda, Brentuximab vedotin, Doxorubicin, Antibody-drug conjugate (ADC) and the tag pipeline.
Shares Prednisone, Doxorubicin, Cyclophosphamide, Antibody-drug conjugate (ADC) and the tag pipeline.
Shares Prednisone, Doxorubicin, Cyclophosphamide, Antibody-drug conjugate (ADC) and the tag pipeline.
Shares Takeda, Non-Hodgkin lymphoma (all types) and the tag pipeline.
Shares Prednisone, Doxorubicin, Cyclophosphamide, Non-Hodgkin lymphoma (all types) and the tag pipeline.
Shares Prednisone, Doxorubicin, Cyclophosphamide, Non-Hodgkin lymphoma (all types) and the tag pipeline.
Shares Prednisone, Doxorubicin, Cyclophosphamide and the tag pipeline.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/