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A phase 2/3 trial of dexamethasone, docetaxel, gemcitabine, pembrolizumab and other drugs in lung cancer, run by SWOG Cancer Research Network, active but no longer recruiting.
Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) is a phase 2/3, randomised interventional study registered as NCT05096663 by SWOG Cancer Research Network, with a registry enrolment figure of 82 participants, started 2022-03-15 and due to reach its primary completion in 2027-06-30. Interventions recorded: Cobalamin; Dexamethasone; Docetaxel; Folic Acid; Gemcitabine; Nogapendekin Alfa; Pembrolizumab; Pemetrexed; Ramucirumab. Conditions listed: Advanced Lung Non-Small Cell Carcinoma; Recurrent Lung Non-Small Cell Carcinoma; Stage III Lung Cancer AJCC v8; Stage IIIA Lung Cancer AJCC v8; Stage IIIB Lung Cancer AJCC v8; Stage IIIC Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8; Stage IVA Lu. Primary outcome: Overall survival. Lung eligibility wording from the registry: "Assignment to S1800D is determined by the LUNGMAP or S1400 protocol". Sites: United States. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Ramucirumab, Dexamethasone, Docetaxel, Anti-angiogenic therapy and the tag lung-deep-dive.
Shares Pemetrexed, Docetaxel, Anti-angiogenic therapy, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Pembrolizumab, Cytotoxic chemotherapy and the tag lung-deep-dive.
Shares Pemetrexed, Docetaxel, Anti-angiogenic therapy, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Pembrolizumab, Cytotoxic chemotherapy and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Pembrolizumab, Cytotoxic chemotherapy and the tag lung-deep-dive.
Shares Ramucirumab, Docetaxel, Anti-angiogenic therapy, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Anti-angiogenic therapy, Lung cancer trials open today (registry snapshot), Pembrolizumab, Cytotoxic chemotherapy and the tag lung-deep-dive.
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