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A phase 2 trial of Ziv-aflibercept, Irinotecan and Fluorouracil in Colorectal cancer, run by Sanofi, completed.
A Study of Aflibercept in Combination With FOLFIRI in Patients With Second-Line Metastatic Colorectal Cancer in Japan is a phase 2 interventional study registered as NCT01882868 by Sanofi, with 62 participants recorded, started 2013-07 and reaching its primary completion in 2015-08. Interventions recorded: Aflibercept, Levofolinate, Irinotecan, 5-FU. Conditions recorded: Colorectal Cancer Metastatic.
Linked to the drug Ziv-aflibercept because the registry names it among its interventions and Colorectal cancer among its conditions. Registry record only: no result has been read by an editor.
Numbers are from the trial as recorded here; see the source links in the table below. This is orientation, not medical advice: ask your team how closely the trial population matches you.
62 enrolled.
95% CI 1.3 to 15.3; Figures from the ClinicalTrials.gov results section (first posted 2017-03-14), not from a publication
Source95% CI 11.203 to 19.811; Figures from the ClinicalTrials.gov results section (first posted 2017-03-14), not from a publication
Source95% CI 4.140 to 6.702; Figures from the ClinicalTrials.gov results section (first posted 2017-03-14), not from a publication
SourceThe full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Irinotecan (and liposomal irinotecan), Fluorouracil (5-FU), Colorectal cancer and the tag pipeline.
Shares Ziv-aflibercept and the tag pipeline.
Shares Irinotecan (and liposomal irinotecan), Fluorouracil (5-FU), Colorectal cancer and the tag pipeline.
Shares Fluorouracil (5-FU), Colorectal cancer and the tag pipeline.
Shares Irinotecan (and liposomal irinotecan), Fluorouracil (5-FU), Colorectal cancer and the tag pipeline.
Shares Irinotecan (and liposomal irinotecan), Fluorouracil (5-FU), Colorectal cancer and the tag pipeline.
Shares Sanofi, Colorectal cancer and the tag pipeline.
Shares Irinotecan (and liposomal irinotecan), Colorectal cancer and the tag pipeline.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/