A phase 3 trial of Shark cartilage in Lung cancer and Non-small-cell lung cancer, run by National Cancer Institute (NCI), completed.
Combination Chemotherapy Plus Radiation Therapy With or Without AE-941 in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed By Surgery is a phase 3 interventional study registered as NCT00005838 by National Cancer Institute (NCI), with 756 participants recorded, started 2000-03 and reaching its primary completion in 2007-02. Interventions recorded: shark cartilage extract AE-941, placebo, cisplatin, vinorelbine tartrate, carboplatin, paclitaxel, radiation therapy. Conditions recorded: Adenocarcinoma of the Lung, Adenosquamous Cell Lung Cancer, Large Cell Lung Cancer, Squamous Cell Lung Cancer, Stage IIIA Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer.
Linked to the technology Shark cartilage because the registry names it ("shark cartilage") among its interventions and Lung cancer and Non-small-cell lung cancer among its conditions. Registry record only: no result has been read by an editor.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Vinorelbine, Paclitaxel / nab-paclitaxel, Cisplatin, Non-small-cell lung cancer and the tag pipeline.
Shares Unresectable stage III non-small-cell lung cancer, Cisplatin, Carboplatin, Non-small-cell lung cancer and the tag pipeline.
Shares Paclitaxel / nab-paclitaxel, Cisplatin, Carboplatin, Lung cancer (all types) and the tag pipeline.
Shares Unresectable stage III non-small-cell lung cancer, Carboplatin, Non-small-cell lung cancer and the tag pipeline.
Shares Shark cartilage (AE-941, Neovastat) and the tag pipeline.
Shares Paclitaxel / nab-paclitaxel, Cisplatin, Carboplatin and the tag pipeline.
Shares Cisplatin, Carboplatin, Non-small-cell lung cancer and the tag pipeline.
Shares Cisplatin, Carboplatin, Non-small-cell lung cancer and the tag pipeline.
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