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Radiobiologist who discovered the FLASH effect: ultra-fast radiation spares healthy tissue while still killing tumours.
Marie-Catherine Vozenin led the 2014 study showing that radiation delivered at ultra-high dose rates (over 40 Gy per second) spares normal lung tissue in mice while retaining anti-tumour efficacy, the FLASH effect, and went on to confirm it in mini-pigs, cats and the first human patient with Jean Bourhis. Her work launched a global effort to build FLASH-capable machines and understand the underlying biology.
| Title | Journal | Year |
|---|---|---|
| Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice | Science Translational Medicine | 2014 |
| The advantage of FLASH radiotherapy confirmed in mini-pig and cat-cancer patients | Clinical Cancer Research | 2019 |
Shares Lausanne University Hospital (CHUV) / Ludwig Institute Lausanne, FLASH radiotherapy and the tags radiotherapy, flash.
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