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Sunnybrook Odette Cancer Centre
One of Canada's largest cancer centres, where focused ultrasound first opened the blood-brain barrier in a patient and Canada's first MR-linac was installed.
Also called: Odette Cancer CentreSunnybrook Health Sciences Centre
Overview
The Odette Cancer Centre at Sunnybrook Health Sciences Centre is one of Canada's largest cancer programmes and a University of Toronto teaching site. Sunnybrook Research Institute's Kullervo Hynynen pioneered MR-guided focused ultrasound, and in 2015 neurosurgeon Todd Mainprize used it to open the blood-brain barrier non-invasively in a brain tumour patient for the first time, work now in trials for glioblastoma and brain metastases with Insightec. Radiation oncology is a signature strength: Arjun Sahgal led the CCTG SC.24 trial of stereotactic radiotherapy for spinal metastases, Gregory Czarnota develops ultrasound-stimulated microbubble radiosensitisation, and Sunnybrook installed Canada's first MR-linac. The Odette Breast Centre and a large GU programme (including prostate brachytherapy) complete the picture.
Location
Toronto, ON, CA
Type
cancer center · University of Toronto
Newsweek 2026 oncology rank
Not in top 300 listing used
OnCo score
#109 · 38 points (0 Newsweek + 0 NCI + 38 from 19 linked objects) · ranking
Research output
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-10-15.
Matched to Odette Cancer Centre, including child institutions. 235 works · 2,229 citations · 65% open access · 11% clinical trials · 10% reviews.
Oncology works per year
612022
522023
332024
442025
452026
Most works
- Kelvin Chan35 works
- Julie I. Hallet30 works
- Rinku Sutradhar24 works
- Natalie G. Coburn24 works
- Henry C. Y. Wong22 works
- Monika Krzyzanowska21 works
- Antoine E. Eskander20 works
- Andrea F. Eisen18 works
- Muna Alkhaifi17 works
- Shing Fung Lee16 works
Most cited
Programmes
4- Focused ultrasound and blood-brain barrier opening
- MR-linac and stereotactic radiotherapy
- Breast cancer
- Genitourinary oncology
People
2Monika Krzyzanowska
Chief, Odette Cancer Program, Sunnybrook Health Sciences Centre
Medical oncologyHealth services researchQuality of cancer care
Medical oncologist and health services researcher who leads the Odette Cancer Program at Sunnybrook in Toronto, one of Canada's largest cancer centres.
Simron Singh
Medical Oncologist and Co-Director, Susan Leslie Clinic for Neuroendocrine Tumours, Sunnybrook Odette Cancer Centre
Neuroendocrine tumoursRadioligand therapyHealth services research
Led NETTER-2, which moved lutetium dotatate into first-line treatment of higher-grade neuroendocrine tumours.
Connected
21Similar pages
- TechnologySonodynamic therapy
Shares Insightec, Transcranial focused ultrasound systems (Exablate Neuro, SonoCloud), Focused-ultrasound blood-brain barrier opening, Focused ultrasound & histotripsy.
- IdeaA standard platform to get drugs into the brain: focused ultrasound plus shuttle-engineered therapeutics
Shares Insightec, Focused ultrasound & histotripsy, The brain: barrier and sanctuary, Glioma & glioblastoma.
- IdeaUltrasound-assisted blood test instead of a brain biopsy
Shares Insightec, Focused-ultrasound blood-brain barrier opening, The brain: barrier and sanctuary, Glioma & glioblastoma.
- IdeaOpen the barrier so engineered immune cells can enter the brain
Shares Insightec, Focused-ultrasound blood-brain barrier opening, The brain: barrier and sanctuary, Glioma & glioblastoma.
- InstitutionJuravinski Cancer Centre / Escarpment Cancer Research Institute
Shares Ontario Health (Cancer Care Ontario), Canadian Cancer Trials Group (CCTG), Glioma & glioblastoma, HR-positive / HER2-negative breast cancer.
- InstitutionUVA Comprehensive Cancer Center
Shares Insightec, Focused-ultrasound blood-brain barrier opening, Focused ultrasound & histotripsy.
- CompanyCarthera
Shares Transcranial focused ultrasound systems (Exablate Neuro, SonoCloud), Focused-ultrasound blood-brain barrier opening, Glioma & glioblastoma.
- CompanyAlpha Tau Medical
Shares Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants, Brachytherapy, Glioma & glioblastoma, Prostate cancer.
cancers
technologies
BrachytherapyFocused ultrasound & histotripsyFocused-ultrasound blood-brain barrier openingGamma KnifeMR-guided adaptive radiotherapySBRT / SABR (stereotactic radiotherapy)Stereotactic radiosurgery (Gamma Knife, CyberKnife, linac SRS)Transcranial focused ultrasound systems (Exablate Neuro, SonoCloud)
companies
institutions
terms
roadmaps
people
bottlenecks
Sources
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
sunnybrook.ca · 2
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