A Department of Biotechnology institute in Bengaluru that develops stem cell and gene editing approaches to cancer and blood disorders, and shares a campus with NCBS.
inStem was established in 2009 as an autonomous institute of the Department of Biotechnology and now sits under the Biotechnology Research and Innovation Council. Its stated focus is cellular therapies for cancer, cardiovascular and neurodegenerative disease, using stem cell biology, disease modelling, CRISPR-based gene editing and bioinformatics. It is part of the Bangalore Life Science Cluster with NCBS and C-CAMP, collaborates with CMC Vellore's Centre for Stem Cell Research on haematological gene therapy, and had a budget of about 60.6 crore rupees in 2022-23.
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-10-08.
Matched to Institute for Stem Cell Biology and Regenerative Medicine, including child institutions. 4 works · 116 citations · 75% open access · 0% clinical trials · 0% reviews.
| Work | Journal | Year | Citations |
|---|---|---|---|
| Microbial metabolite restricts 5-fluorouracil-resistant colonic tumor progression by sensitizing drug transporters via regulation of FOXO3-FOXM1 axis 10.7150/thno.70754 · open access | Theranostics | 2022 | 85 |
| Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin 10.1016/j.celrep.2022.111390 · open access | Cell Reports | 2022 | 16 |
| Challenges in Global Access to CAR-T cells: an Asian Perspective 10.31547/bct-2023-023 · open access | BLOOD CELL THERAPY / The official journal of APBMT | 2024 | 13 |
| Abstract 3250: Microbial metabolite, Urolithin A acts as chemo-sensitizing adjuvant in conventional drug therapies via modulation of drug transporters and EMT markers conference abstract · 10.1158/1538-7445.am2022-3250 | Cancer Research | 2022 | 2 |
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