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Histiocyte Society
The international society of doctors and scientists who study histiocytic disorders; its LCH trials, run since the 1990s, set the worldwide standard for treating Langerhans cell histiocytosis in children.
Overview
Founded in 1985, the Histiocyte Society brings together clinicians and researchers working on Langerhans cell histiocytosis, haemophagocytic lymphohistiocytosis, Erdheim-Chester disease, Rosai-Dorfman disease and juvenile xanthogranuloma. It has run the sequential international LCH-I (1991), LCH-II, LCH-III (2001-2008) and LCH-IV trials, which established vinblastine-prednisone as standard therapy and defined its duration, and the HLH-94 and HLH-2004 protocols. It publishes classification and consensus guidelines, holds an annual scientific meeting, and maintains registries that supported the recognition of histiocytoses as MAPK-driven clonal neoplasms.
Location
Pitman, US
Type
consortium
Website
Newsweek 2026 oncology rank
Not in top 300 listing used
OnCo score
#437 · 10 points (0 Newsweek + 0 NCI + 10 from 5 linked objects) · ranking
Programmes
4- LCH-I to LCH-IV international trials
- HLH-94 and HLH-2004 protocols
- Histiocytosis classification and consensus guidelines
- Annual meeting and registries
People
1Connected
6Similar pages
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cancers
drugs
ApprovedVinca alkaloid (microtubule inhibitor)
Vinblastine · Velban
trials
people
bottlenecks
Sources
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
histiocytesociety.org · 1
A source that has moved or gone is reported by the weekly link check. /audit/
ProvenanceLast edited 2026-09-11 · Jude Gomila · Link orphan journals, startups, investors, collections an… · diff · file
Sourced, not expert-reviewed