Pay a fixed reward to any lab that pre-registers and carefully repeats a heavily cited preclinical cancer finding, whatever the outcome, with a bonus for the first documented non-replication that passes methodological review. Today that work is unpaid and unpublished.
Security research uses bug bounties to reward finding flaws. A replication bounty programme would list high-impact preclinical oncology findings (selected by citations and translational stage), pay a fixed sum for a pre-registered, adequately powered replication attempt regardless of outcome, and a bonus for the first documented non-replication that passes methodological review. Results are published in a registry.
Shares A replication status badge on every cancer paper, visible in PubMed, Funders set aside a fixed share of budget for independent replication, Preclinical results do not reproduce.
Shares A registry for preclinical experiments that did not work, Preclinical results do not reproduce, Failures are hidden.
Shares A replication status badge on every cancer paper, visible in PubMed, Preclinical results do not reproduce, Failures are hidden.
Shares Funders set aside a fixed share of budget for independent replication, Preclinical results do not reproduce.
Shares A registry for preclinical experiments that did not work, Failures are hidden.
Shares A registry for preclinical experiments that did not work, Failures are hidden.
Shares A registry for preclinical experiments that did not work, Failures are hidden.
Shares Preclinical results do not reproduce, Failures are hidden.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/