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Insys Therapeutics
Insys Therapeutics was an Arizona company whose sublingual fentanyl spray for breakthrough cancer pain went through phase 3 trials; its marketing practices later led to criminal convictions and bankruptcy.
Also called: INSYS Therapeutics IncInsys Therapeutics, Inc.
Overview
Insys Therapeutics, founded in 1990 and based in Chandler, Arizona, developed Subsys, a fentanyl sublingual spray approved for breakthrough pain in opioid-tolerant cancer patients, and a dronabinol oral solution. Its executives were convicted in 2019 over kickbacks to prescribers, and the company filed for bankruptcy the same year. Its phase 3 trials in cancer pain remain on ClinicalTrials.gov under Insys as lead sponsor. ClinicalTrials.gov also lists under Insys the earlier NeoPharm programmes it absorbed, including the interleukin-13 conjugated toxin IL13-PE38QQR (cintredekin besudotox) in malignant glioma (NCT00076986) and liposomal paclitaxel and docetaxel formulations.
Headquarters
Chandler, AZ, US
Scorecard
All companies#185of 1245 companies, score 32
- targets +2
- modalities +2
- regions +1
- registry trials +27
0 approved, 0 in phase 3, 0 earlier, 1 targets, 180 registry studies. Formula on the scorecards page.
Type
Stage
Wound down
Website
Founded
1990
Products
1EstablishedOral small-molecule synthetic cannabinoid
Dronabinol · Marinol / Syndros
Dronabinol is synthetic THC in a capsule, approved in 1985 for chemotherapy nausea and vomiting that other antiemetics have failed to control, and later for appetite loss in AIDS; it sits well behind the 5-HT3 and NK1 antagonists in today's guidelines.
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cancers
fronts
technologies
drugs
EstablishedOral small-molecule synthetic cannabinoid
Dronabinol · Marinol / Syndros
terms
Sources
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
ClinicalTrials.gov · 1
insysrx.com · 1
wikidata.org · 1
A source that has moved or gone is reported by the weekly link check. /audit/
ProvenanceLast edited 2026-09-18 · Jude Gomila · Add Wikidata ids and Wikipedia links for 80 more companies · diff · file
Sourced, not expert-reviewed