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HOVON
The Dutch-Belgian adult haematology trials group, one of Europe's largest engines of leukaemia, myeloma and lymphoma phase 3 trials.
Also called: Haemato Oncology Foundation for Adults in the NetherlandsStichting Hemato-Oncologie voor Volwassenen Nederland
Overview
Founded in 1985 and coordinated from Rotterdam, HOVON runs trials across the Netherlands, Belgium and partner countries, often jointly with the Swiss SAKK and the German and Nordic groups. Its AML trials defined intensive induction, consolidation and transplant strategies in adults and the elderly, HOVON-65/GMMG-HD4 established bortezomib in myeloma induction and maintenance, and HOVON lymphoma and CLL studies contribute to European standards. HOVON participates in the European Myeloma Network trials and runs a national data centre and biobank. Most Dutch adults with acute leukaemia are treated within or according to a HOVON protocol.
Headquarters
Rotterdam, NL
Scorecard
All companies#119of 1245 companies, score 46
- approved products +6
- targets +2
- modalities +2
- regions +6
- registry trials +30
1 approved, 0 in phase 3, 0 earlier, 1 targets, 566 registry studies. Formula on the scorecards page.
Website
Founded
1985
Research output
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-10-08.
Matched to Hovon, including child institutions. 4 works · 122 citations · 50% open access · 50% clinical trials · 0% reviews.
Oncology works per year
42022
02023
02024
02025
02026
Most works
- Marie José Kersten4 works
- Ram K. Malladi2 works
- Catherine Thiéblemont2 works
- Stephen J. Schuster2 works
- Julio C. Chávez2 works
- Reem Karmali1 works
- Mahmoud Elsawy1 works
- Marcela Martínez-Prieto1 works
- Davide Germano1 works
- Leslie L. Popplewell1 works
Most cited
| Work | Journal | Year | Citations |
|---|---|---|---|
| Patient-reported outcomes in ZUMA-7, a phase 3 study of axicabtagene ciloleucel in second-line large B-cell lymphoma 10.1182/blood.2022015478 · open access | Blood | 2022 | 80 |
| Long-Term Clinical Outcomes and Correlative Efficacy Analyses in Patients (Pts) with Relapsed/Refractory Follicular Lymphoma (r/r FL) Treated with Tisagenlecleucel in the Elara Trial 10.1182/blood-2022-158024 | Blood | 2022 | 20 |
| Comparative efficacy of tisagenlecleucel and lisocabtagene maraleucel among adults with relapsed/refractory large B-cell lymphomas: an indirect treatment comparison 10.1080/10428194.2021.2010069 · open access | Leukemia & lymphoma/Leukemia and lymphoma | 2022 | 20 |
| Assessment of Durable Responses after Brexucabtagene Autoleucel (KTE-X19) in the ZUMA-2 Study in Relapsed/Refractory Mantle Cell Lymphoma (R/R MCL) 10.1182/blood-2022-158097 | Blood | 2022 | 2 |
People
3Marc H.G.P. Raaijmakers
Vice Chair
Myelodysplastic syndromesBone marrow niche biologyHaematology
Erasmus MC haematologist and HOVON Vice Chair known for research on the bone marrow microenvironment in MDS.
Nicolaas P.M. Schaap
Chair
HaematologyStem cell transplantationCellular therapy
Radboudumc haematologist who chairs HOVON, the Dutch-Belgian haemato-oncology cooperative group.
Pieter Sonneveld
Professor of Hematology, Erasmus MC Cancer Institute; Chair, European Myeloma Network
Multiple myelomaTransplant-eligible myelomaDaratumumab quadruplets
Led PERSEUS, which established daratumumab-VRd as the standard for transplant-eligible myeloma.
Notes
- AML trials (with SAKK)
- Myeloma (HOVON-65/GMMG-HD4, EMN trials)
- Lymphoma and CLL
- National haematology data centre
Connected
21Similar pages
- CompanyLYSA (The Lymphoma Study Association)
Shares German Lymphoma Alliance, International Extranodal Lymphoma Study Group, Hodgkin lymphoma, Diffuse large B-cell lymphoma and the tag cooperative-group.
- CompanyGerman Hodgkin Study Group
Shares German Lymphoma Alliance, Hodgkin lymphoma and the tag cooperative-group.
- CompanyAustralasian Gastro-Intestinal Trials Group
Shares Minimal / molecular residual disease (MRD), MRD / molecular residual disease testing and the tag cooperative-group.
- CompanyChildren's Cancer and Leukaemia Group
Shares MRD / molecular residual disease testing, Acute lymphoblastic leukaemia and the tag cooperative-group.
- CompanyALFA (Acute Leukemia French Association)
Shares Acute myeloid leukaemia and the tag cooperative-group.
- CompanyEuropean Myeloma Network
Shares Multiple myeloma and the tag cooperative-group.
- CompanyFILO (French Innovative Leukemia Organisation)
Shares Acute myeloid leukaemia and the tag cooperative-group.
- CompanyGerman CLL Study Group
Shares Chronic lymphocytic leukaemia and the tag cooperative-group.
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ApprovedSmall-molecule BCL-2 inhibitor
Venetoclax · Venclexta
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