# OnCo record palacaparib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/palacaparib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "palacaparib" ;
  schema:name "Palacaparib"@en ;
  schema:description "Palacaparib is an experimental DNA-repair inhibitor designed to reach the brain and selectively block PARP1."@en ;
  schema:url <https://onco.cc/drugs/palacaparib/> ;
  schema:dateModified "2026-10-06"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/search?intr=AZD9574>, <https://clinicaltrials.gov/study/NCT05417594>, <https://doi.org/10.1021/acs.jmedchem.4c01725> ;
  onco:status "phase-2" ;
  onco:tag "pipeline", "ctgov-ingest" ;
  onco:modality "small molecule" ;
  onco:cancers <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/endometrial/> ;
  onco:targets <https://onco.cc/targets/parp/> ;
  onco:companies <https://onco.cc/companies/astrazeneca/> ;
  onco:trials <https://onco.cc/trials/nct07181161/>, <https://onco.cc/trials/nct05797168/>, <https://onco.cc/trials/nct05123482/>, <https://onco.cc/trials/nct07590934/>, <https://onco.cc/trials/nct05417594/> .