# OnCo record lobular-carcinoma-in-situ (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/lobular-carcinoma-in-situ/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "lobular-carcinoma-in-situ" ;
  schema:name "Lobular carcinoma in situ (LCIS)"@en ;
  schema:alternateName "LCIS"@en, "Lobular neoplasia"@en, "Classic lobular carcinoma in situ"@en, "Pleomorphic lobular carcinoma in situ"@en, "Florid lobular carcinoma in situ"@en, "Atypical lobular hyperplasia (lesser form)"@en, "Tis (LCIS)"@en, "stage 0 lobular"@en, "lobular neoplasia"@en, "in situ lobular carcinoma"@en ;
  schema:description "Lobular carcinoma in situ is not an invasive breast cancer but a marker that a woman is at higher risk of one: abnormal cells fill the milk-producing lobules without spreading. About one in five women develop breast cancer within ten years, in either breast and of any type; preventive tamoxifen cuts that to about one in fourteen, and the pleomorphic form is excised like ductal carcinoma in situ."@en ;
  schema:url <https://onco.cc/cancers/lobular-carcinoma-in-situ/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Lobular_carcinoma_in_situ> ;
  schema:citation <https://doi.org/10.1111/his.14091>, <https://doi.org/10.1200/jco.2015.61.4743>, <https://doi.org/10.1245/s10434-015-4552-x>, <https://www.cancerresearchuk.org/about-cancer/breast-cancer/types>, <https://www.rcpath.org/resourceLibrary/g148-dataset-for-histopathological-reporting-of-breast-disease-in-surgical-excision-specimens-of-breast-cancer.html> ;
  onco:tag "subtype-page", "wave4", "breast" ;
  onco:related <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/ductal-carcinoma-in-situ/>, <https://onco.cc/cancers/invasive-lobular-carcinoma/>, <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:targets <https://onco.cc/targets/cdh1/> ;
  onco:drugs <https://onco.cc/drugs/tamoxifen/> ;
  onco:terms <https://onco.cc/terms/aromatase-inhibitor/>, <https://onco.cc/terms/carcinoma-in-situ/>, <https://onco.cc/terms/mastectomy/>, <https://onco.cc/terms/tnm-breast-cancer-editions/>, <https://onco.cc/terms/terminal-duct-lobular-unit/>, <https://onco.cc/terms/who-breast-classification/> ;
  onco:trials <https://onco.cc/trials/tam-01/> ;
  onco:standardOfCare <https://onco.cc/drugs/tamoxifen/>, <https://onco.cc/trials/tam-01/>, <https://onco.cc/terms/aromatase-inhibitor/>, <https://onco.cc/cancers/ductal-carcinoma-in-situ/>, <https://onco.cc/terms/mastectomy/> .