# OnCo record geparsixto (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/geparsixto/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "geparsixto", "NCT01426880" ;
  schema:name "GeparSixto"@en ;
  schema:alternateName "GBG 66"@en ;
  schema:description "GeparSixto showed that adding carboplatin to chemotherapy given before surgery made triple-negative breast tumours disappear completely far more often, and in longer follow-up cut relapses, which put platinum into the standard neoadjuvant regimen for this type."@en ;
  schema:url <https://onco.cc/trials/geparsixto/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01426880>, <https://doi.org/10.1093/annonc/mdy460> ;
  onco:status "positive" ;
  onco:tag "subtype-trials" ;
  onco:phase "2/3" ;
  schema:startDate "2011-08" ;
  onco:cancers <https://onco.cc/cancers/tnbc-early/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/breast-cancer/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/platinum/> ;
  onco:drugs <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/bevacizumab/>, <https://onco.cc/drugs/trastuzumab/>, <https://onco.cc/drugs/lapatinib/> ;
  onco:companies <https://onco.cc/companies/gbg/> ;
  onco:trials <https://onco.cc/trials/brightness/>, <https://onco.cc/trials/calgb-40603/>, <https://onco.cc/trials/keynote-522/> ;
  onco:people <https://onco.cc/people/gunter-von-minckwitz/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-hahnen-geparsixto-germline-brca-jama-oncol-2017/>, <https://onco.cc/key-papers/paper-loibl-geparsixto-survival-hrd-ann-oncol-2018/>, <https://onco.cc/key-papers/paper-geparsixto-lancet-oncol-2014/> .