# OnCo record bcl6 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/bcl6/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "bcl6" ;
  schema:name "BCL6"@en ;
  schema:alternateName "BCL6 transcription repressor"@en, "B-cell lymphoma 6 protein"@en, "ZBTB27"@en, "LAZ3"@en, "BCL5"@en, "BCL6A"@en, "ZNF51"@en, "BCL6" ;
  schema:description "BCL6 (B-cell lymphoma 6 protein) is a protein that switches other genes on and off. The public catalogues list it as an oncogene driver, a tumour suppressor, a biomarker and a fusion partner, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Non-Hodgkin lymphoma, Lung cancer, Myeloproliferative neoplasms and 3 more."@en ;
  schema:url <https://onco.cc/targets/bcl6/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001>, <https://www.uniprot.org/uniprotkb/P41182/entry>, <https://www.ncbi.nlm.nih.gov/gene/604>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000113916>, <https://doi.org/10.1073/pnas.79.24.7824>, <https://doi.org/10.1182/blood-2012-06-435842>, <https://doi.org/10.1200/JCO.2011.41.0985>, <https://doi.org/10.1038/s41375-022-01620-2>, <https://doi.org/10.1056/NEJMoa1801445> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  onco:firstDescribed "1993"^^xsd:gYear ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000113916>, <https://www.uniprot.org/uniprotkb/P41182/entry>, <https://www.ncbi.nlm.nih.gov/gene/604> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/myeloproliferative-neoplasms/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/dlbcl/> ;
  onco:pathways <https://onco.cc/pathways/myc/>, <https://onco.cc/pathways/transcription-addiction/>, <https://onco.cc/pathways/epigenetic-reprogramming/> .