{"entity":{"id":"vb15010","kind":"drug","name":"VB15010","aka":[],"tldr":"VB15010 is an experimental pill targeting the PARP1 DNA-repair enzyme.","summary":"NCT06819215 is a recruiting phase 1/2 study of VB15010 in advanced solid tumours. The registry describes PARP1 inhibition; there is no marketing approval or comparative clinical efficacy claim here.","status":"phase-2","asOf":"2026-10-06","links":[{"label":"ClinicalTrials.gov: trials of VB15010","url":"https://clinicaltrials.gov/search?intr=VB15010"},{"label":"ClinicalTrials.gov NCT06819215","url":"https://clinicaltrials.gov/study/NCT06819215"}],"tags":["pipeline","ctgov-ingest","registry-only"],"related":[],"cancers":["ovarian","prostate","pancreatic","cholangiocarcinoma","colorectal"],"sections":[],"technologies":[],"targets":["parp"],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":["nct06819215"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2, registry-only)","editedOn":"2026-09-16"},"code":"VB15010","modality":"Small-molecule inhibitor","mechanism":"The registry describes VB15010 as a PARP1 inhibitor.","approvals":[],"mechanismSteps":[],"toxicity":[],"access":[],"regulatoryEvents":[]},"route":"/drugs/vb15010/","neighbours":{"cancer":[{"id":"cholangiocarcinoma","kind":"cancer","name":"Biliary tract cancer (cholangiocarcinoma)","route":"/cancers/cholangiocarcinoma/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"},{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"target":[{"id":"parp","kind":"target","name":"PARP","route":"/targets/parp/"}],"trial":[{"id":"nct06819215","kind":"trial","name":"Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors","route":"/trials/nct06819215/"}]}}