{"entity":{"id":"nct07734116","kind":"trial","name":"A Study of ONO-4538HSC in Pediatric Patients With Malignant Solid Tumors and in Patients With Epithelioid Sarcoma.","aka":[],"tldr":"A phase 1/2 trial of ONO-4538HSC in epithelioid sarcoma, run by Ono Pharmaceutical Co., Ltd., now recruiting.","summary":"A Study of ONO-4538HSC in Pediatric Patients With Malignant Solid Tumors and in Patients With Epithelioid Sarcoma. is a phase 1/2 interventional study registered as NCT07734116 by Ono Pharmaceutical Co., Ltd., with 50 participants planned, started 2026-08-18 and due to reach its primary completion in 2029-11-30. Interventions recorded: ONO-4538HSC.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07734116","url":"https://clinicaltrials.gov/study/NCT07734116"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["epithelioid-sarcoma"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["deciphera"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07734116","phase":"1/2","setting":"A Multicenter, Open-label, Uncontrolled Phase I/II Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ONO-4538HSC in Pediatric Patients With Malignant Solid Tumors and in Patients With Epithelioid Sarcoma, and to Evaluate the Tolerability in Pediatric Patients.","sponsor":"Ono Pharmaceutical Co., Ltd.","participation":[{"nct":"NCT07734116","source":"https://clinicaltrials.gov/study/NCT07734116","fetchedAt":"2026-10-07T16:56:10.647Z","studySha256":"0589b9300bb941d9069731e2d7d165742bd5bff068f1c0235e838ba2cfddfe25","overallStatus":"RECRUITING","lastUpdatePosted":"2026-10-06","leadSponsor":"Ono Pharmaceutical Co., Ltd.","collaboratorCount":0,"minimumAge":"12 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":50,"enrolmentType":"ESTIMATED","siteCount":15,"recruitingSiteCount":6,"countries":["Japan"]}],"started":"2026-08-18","startedType":"actual","enrolled":50,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07734116/","neighbours":{"cancer":[{"id":"epithelioid-sarcoma","kind":"cancer","name":"Epithelioid sarcoma","route":"/cancers/epithelioid-sarcoma/"}],"company":[{"id":"deciphera","kind":"company","name":"Deciphera Pharmaceuticals (Ono)","route":"/companies/deciphera/"}]}}